Hypoparathyroidism & Free Siddha Energy Remedies

Hypoparathyroidism Definition (???????????? ?? ???????)

It is the diminished concentration of the parathyroid hormone in the blood, which causes deficiencies of calcium and phosphorus compounds in the blood and results in muscular spasms.

 

Hypoparathyroidism Symptoms (???????????? ?? ?????)

The main symptoms of hypoparathyroidism are the result of the low blood calcium level, which interferes with normal muscle contraction and nerve conduction. As a result, people with hypoparathyroidism can experience paresthesia, an unpleasant tingling sensation around the mouth and in the hands and feet, as well as muscle cramps and severe spasms known as “tetany” that affect the hands and feet. 

Many also report a number of subjective symptoms such as:

• Fatigue
• Headaches
• Bone pain
• Insomnia

Crampy abdominal pain may occur. Physical examination of someone with hypocalcemia may show tetany, but it is also possible to provoke tetany of the facial muscles by tapping on the facial nerve or by using the cuff of a sphygmomanometer to temporarily obstruct the blood flow to the arm.

A number of medical emergencies can arise in people with low calcium levels. These are seizures, severe irregularities in the normal heartbeat, as well as spasm of the upper part of the airways or the smaller airways known as the bronchi, both potentially causing respiratory failure.

Hypoparathyroidism Causes (???????????? ?? ????)

Hypoparathyroidism can have the following causes:

• Removal of, or trauma to, the parathyroid glands due to thyroid surgery, parathyroid surgery or other surgical interventions in the central part of the neck is a recognized cause
• Kenny-Caffey Syndrome
• Autoimmune invasion and destruction is the most common non-surgical cause
• Hemochromatosis can lead to iron accumulation and consequent dysfunction of a number of endocrine organs, including the parathyroids
• Absence or dysfunction of the parathyroid glands is one of the components of chromosome 22q11 microdeletion syndrome 
• Magnesium deficiency
• A defect in the calcium receptor leads to a rare congenital form of the disease
• Idiopathic, occasionally familial e.g. Barakat syndrome a genetic developmental disorder resulting in hypoparathyroidism, sensorineural deafness, and kidney disease

Hypoparathyroidism Mechanism (???????????? ?? ?????)

The parathyroid glands are so named because they are usually located behind the thyroid gland in the neck. They arise during fetal development from structures known as the third and fourth pharyngeal pouch. The glands, usually four in number, contain the parathyroid chief cells that sense the level of calcium in the blood through the calcium-sensing receptor and secrete parathyroid hormone. 

PTH acts on several organs to increase calcium levels. It increases calcium absorption in the bowel, while in the kidney it prevents calcium excretion and increases phosphate release and in the bone, it increases calcium through bone resorption.

Hypoparathyroidism Diagnosis (???????????? ?? ?????)

Diagnosis is by measurement of calcium, serum albumin for correction and PTH in blood.

If necessary, measuring cAMP in the urine after an intravenous dose of PTH can help in the distinction between hypoparathyroidism and other causes.

Differential diagnoses are:

• Pseudohypoparathyroidism, normal PTH levels but tissue insensitivity to the hormone, associated with intellectual disability and skeletal deformities, and pseudopseudohypoparathyroidism
• Vitamin D deficiency or hereditary insensitivity to this vitamin
• Malabsorption
• Kidney disease
• Medication: steroids, diuretics, and some antiepileptics

Other tests include ECG for abnormal heart rhythms and measurement of blood magnesium levels.

Hypoparathyroidism Treatment (???????????? ?? ?????)

In the event of a life-threatening attack of low calcium levels or tetany, calcium is administered by intravenous (IV) infusion. Precautions are taken to prevent seizures or larynx spasms. The heart is monitored for abnormal rhythms until the person is stable.

When the life-threatening attack has been controlled, treatment continues with medicine taken by mouth as often as four times a day.

Long-term treatment of hypoparathyroidism is with vitamin D analogs and calcium supplementation but may be ineffective in some due to potential renal damage. The N-terminal fragment of parathyroid hormone has full biological activity.

The use of pump delivery of synthetic PTH 1-34 provides the closest approach to physiologic PTH replacement therapy. Injections of recombinant human parathyroid hormone are available as a treatment in those with low blood calcium levels.

New Hypoparathyroidism treatment (???????????? ?? ??? ????)

In January, the FDA gave its approval to Natpara for treatment of hypoparathyroidism in patients who cannot be controlled with calcium and active vitamin D supplementation alone. 

Hypoparathyroidism Home remedies (???????????? ?? ????? ?????)

Hypoparathyroidism & Free Siddha energy remedies (????????????

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