Diabetic retinopathy (?????? ??????????), also known as diabetic eye disease (?????? ????? ???), is a medical condition in which damage occurs to the retina due to diabetes mellitus. It is a leading cause of blindness. Diabetic retinopathy affects up to 80% of those who have had diabetes for 20 years or more. At least 90% of new cases could be reduced with proper treatment and monitoring of the eyes. The longer a person has diabetes, the higher his or her chances of developing diabetic retinopathy. Being diabetic retinopathy more risky and dangerous, Siddha Spirituality of Swami Hardas Life System has introduced effective and affordable methods for each and every person in the world. These are free and needs no money and no medicines. Hence, let us know about diabetic retinopathy, symptoms, causes, risk factors, diagnosis, medications, management, stem cell therapy, and most effective Siddha Spirituality of Swami Hardas Life System.
Diabetic retinopathy definition (?????? ?????????? ???????)
Diabetic retinopathy (die-uh-BET-ik ret-ih-NOP-uh-thee) is a diabetes complication that affects eyes. It’s caused by damage to the blood vessels of the light-sensitive tissue at the back of the eye (retina). At first, diabetic retinopathy may cause no symptoms or only mild vision problems.
Diabetic retinopathy symptoms (?????? ?????????? ?? ?????)
Often, there have no early warning signs for Diabetic retinopathy. Even macular edema, which can cause rapid vision loss, may not have any warning signs for some time. In general, however, a person with macular edema is likely to have blurred vision, making it hard to do things like reading or drive. In some cases, the vision will get better or worse during the day.
The first stage, called non-proliferative diabetic retinopathy (NPDR), has no symptoms. Patients may not notice the signs and have 20/20 vision. The only way to detect NPDR is by fundus photography, in which microaneurysms can be seen.
Macular edema, in which blood vessels leak their contents into the macular region, can occur at any stage of NPDR. Its symptoms are blurred vision and darkened or distorted images that are not the same in both eyes.
In the second stage, abnormal new blood vessels form at the back of the eye as part of proliferative diabetic retinopathy (PDR); these can burst and bleed and blur the vision because these new blood vessels are fragile. The first time this bleeding occurs, it may not be very severe. In most cases, it will leave just a few specks of blood, or spots floating in a person’s visual field, though the spots often go away after a few hours.
These spots are often followed within a few days or weeks by a much greater leakage of blood, which blurs the vision. In extreme cases, a person may only be able to tell light from dark in that eye. It may take the blood anywhere from a few days to months or even years to clear from the inside of the eye, and in some cases, the blood will not clear. These types of large hemorrhages tend to happen more than once, often during sleep.
On funduscopic exam, a doctor will see cotton wool spots, flame hemorrhages, and dot-blot hemorrhages.
Diabetic retinopathy Risk factors (?????? ?????????? ?? ????? ??????)
All people with diabetes mellitus are at risk – those with Type I diabetes and those with Type II diabetes. The longer a person has had diabetes, the higher their risk of developing some ocular problem. Between 40 and 45 percent of Americans diagnosed with diabetes have some stage of diabetic retinopathy.
During pregnancy, diabetic retinopathy may also be a problem for women with diabetes. NIH recommends that all pregnant women with diabetes have dilated eye examinations each trimester.
People with Down’s syndrome, who have extra chromosome 21 material, almost never acquire diabetic retinopathy. This protection appears to be due to the elevated levels of endostatin, an anti-angiogenic protein, derived from collagen XVIII. The collagen XVIII gene is located on chromosome 21.
Diabetic retinopathy Diagnosis (?????? ?????????? ?????)
Diabetic retinopathy is detected during an eye examination that includes:
Visual acuity test (????? ????????? ???????)
Uses an eye chart to measure how well a person sees at various distances (i.e., visual acuity).
Pupil dilation (????? ?? ?????)
The eye care professional places drop into the eye to dilate the pupil. This allows him or her to see more of the retina and look for signs of diabetic retinopathy. After the examination, close-up vision may remain blurred for several hours.
Ophthalmoscopy or fundus photography (??????????????? ?? ????? ??????????)
Ophthalmoscopy is an examination of the retina in which the eye care professional:
(1) looks through a slit lamp biomicroscope with a special magnifying lens that provides a narrow view of the retina, or
(2) wearing a headset (indirect ophthalmoscope) with a bright light looks through a special magnifying glass and gains a wide view of the retina. Hand-held ophthalmoscopy is insufficient to rule out significant and treatable diabetic retinopathy.
Fundus photography generally captures considerably larger areas of the fundus and has the advantage of photo documentation for future reference, as well as availing the image to be examined by a specialist at another location and/or time.
Fundus Fluorescein Angiography (FFA) {????? ?????????? ???????????? (?????)}
This is an imaging technique which relies on the circulation of fluorescein dye to show staining, leakage, or non-perfusion of the retinal and choroidal vasculature.
Optical coherence tomography (OCT) {??????? ???????? ?????????? (OCT)}
This is an optical imaging modality based upon interference, and analogous to ultrasound. It produces cross-sectional images of the retina which can be used to measure the thickness of the retina and to resolve its major layers, allowing the observation of swelling.
The eye care professional will look at the retina for early signs of the disease, such as:
- Leaking blood vessels
- Retinal swelling, such as macular edema
- Pale, fatty deposits on the retina – signs of leaking blood vessels
- Damaged nerve tissue (neuropathy)
- Any changes in the blood vessels
If macular edema is suspected, FFA and sometimes OCT may be performed.
Diabetic retinopathy also affects microcirculation through the body. A recent study showed an assessment of conjunctival microvascular hemodynamics such as vessel diameter, red blood cell velocity, and wall shear stress can be useful for diagnosis and screening of diabetic retinopathy.
In April 2018 the FDA approved a similar device called IDx-DR. IDx-DR is an AI diagnostic system that autonomously analyzes images of the retina for signs of diabetic retinopathy.
Google is testing a cloud algorithm that scans photos of the eye for signs of retinopathy. The algorithm still requires FDA approval.
Diabetic retinopathy (DR) is the fastest growing cause of blindness, with nearly 415 million diabetic patients at risk worldwide. If caught early, the disease can be treated; if not, it can lead to irreversible blindness. Unfortunately, medical specialists capable of detecting the disease are not available in many parts of the world where diabetes is prevalent. To read more…
According to a DRSS user manual, poor quality images may be caused by cataract, poor dilation, ptosis, external ocular condition, or learning difficulties. There may be artifacts caused by dust, dirt, condensation, or smudge.
Diabetic retinopathy Screening (?????? ?????????? ????)
In the UK, screening for diabetic retinopathy is part of the standard of care for people with diabetes. After one normal screening in people with diabetes, further screening is recommended every two years. In the UK, this is recommended every year. Teleophthalmology has been employed in these programs.
Diabetic retinopathy Management (?????? ?????????? ???????)
There are three major treatments for diabetic retinopathy, which are very effective in reducing vision loss from this disease. In fact, even people with advanced retinopathy have a 95% chance of keeping their vision when they get treatment before the retina is severely damaged. These three treatments are:
- Laser surgery
- Injection of corticosteroids or anti-VEGF agents into the eye, and
- Vitrectomy
Although these treatments are very successful (in slowing or stopping further vision loss), they do not cure diabetic retinopathy. Caution should be exercised in treatment with laser surgery since it causes a loss of retinal tissue.
It is often more prudent to inject triamcinolone or anti-VEGF drugs. In some patients, it results in a marked increase of vision, especially if there is an edema of the macula.
Avoiding tobacco use and correction of associated hypertension are important therapeutic measures in the management of diabetic retinopathy.
The best way of preventing the onset and delaying the progression of diabetic retinopathy is to monitor it vigilantly and achieve optimal glycemic control.
Laser photocoagulation (???? ???????????????)
Laser photocoagulation can be used in two scenarios for the treatment of diabetic retinopathy. It can be used to treat macular edema by creating a Modified Grid at the posterior pole and it can be used for panretinal coagulation for controlling neovascularization. It is widely used for early stages of proliferative retinopathy.
Modified grid (??????? ?????)
A ‘C’ shaped area around the macula is treated with low-intensity small burns. This helps in clearing the macular edema.
Scatter laser treatment (???? ???? ???? ?????)
Panretinal photocoagulation, or PRP (also called scatter laser treatment), is used to treat proliferative diabetic retinopathy (PDR). The goal is to create 1,600 – 2,000 burns in the retina with the hope of reducing the retina’s oxygen demand, and hence the possibility of ischemia.
In treating advanced diabetic retinopathy, the burns are used to destroy the abnormal blood vessels that form in the retina. This has been shown to reduce the risk of severe vision loss for eyes at risk by 50%.
Before using the laser, the ophthalmologist dilates the pupil and applies anesthetic drops to numb the eye. In some cases, the doctor also may numb the area behind the eye to reduce discomfort. The patient sits facing the laser machine while the doctor holds a special lens on the eye. The physician can use a single spot laser or a pattern scan laser for two-dimensional patterns such as squares, rings, and arcs.
During the procedure, the patient will see flashes of light. These flashes often create an uncomfortable stinging sensation for the patient. After the laser treatment, patients should be advised not to drive for a few hours while the pupils are still dilated. Vision will most likely remain blurry for the rest of the day. Though there should not be much pain in the eye itself, an ice-cream headache like pain may last for hours afterward.
Patients will lose some of their peripheral vision after this surgery although it may be barely noticeable by the patient. The procedure does, however, save the center of the patient’s sight. Laser surgery may also slightly reduce color and night vision.
A person with proliferative retinopathy will always be at risk for new bleeding, as well as glaucoma, a complication from the new blood vessels. This means that multiple treatments may be required to protect vision.
Diabetic retinopathy Medications (?????? ?????????? ?????)
Intravitreal triamcinolone acetonide (?????????????? ?????????????? ?????????)
Triamcinolone is a long-acting steroid preparation. When injected in the vitreous cavity, it decreases the macular edema caused due to diabetic maculopathy and results in an increase in visual acuity. The effect of triamcinolone is transient, lasting up to three months, which necessitates repeated injections for maintaining the beneficial effect.
Best results of intravitreal Triamcinolone have been found in eyes that have already undergone cataract surgery. Complications of intravitreal injection of triamcinolone include:
- Cataract (??????????)
- Steroid-induced glaucoma (???????? ?? ??????? ??? ?? ???)
- Endophthalmitis (????????????)
A systematic review found evidence that eyes treated with the intravitreal injection of triamcinolone had better visual acuity outcomes compared to eyes treated with macular laser grid photocoagulation, or sham injections.
Intravitreal anti-VEGF (?????????????? ????-???????)
There are good results from multiple doses of intravitreal injections of anti-VEGF drugs such as bevacizumab. A 2017 systematic review update found moderate evidence that aflibercept may have advantages in improving visual outcomes over bevacizumab and ranibizumab, after one year. Present recommended treatment for diabetic macular edema is Modified Grid laser photocoagulation combined with multiple injections of anti-VEGF drugs (anti-Vascular Endothelial Growth Factor).
Diabetic retinopathy Surgery (?????? ?????? ?????????? ????-????????)
Instead of laser surgery, some people require a vitrectomy to restore vision. A vitrectomy is performed when there is a lot of blood in the vitreous. It involves removing the cloudy vitreous and replacing it with a saline solution.
Studies show that people who have a vitrectomy soon after a large hemorrhage are more likely to protect their vision than someone who waits to have the operation. Early vitrectomy is especially effective in people with insulin-dependent diabetes, who may be at greater risk of blindness from a hemorrhage into the eye.
Diabetic retinopathy Research (?????? ?????????? ????????)
Light treatment (?????? ?????)
A medical device comprising a mask that delivers green light through the eyelids while a person sleeps was under development in 2016. The light from the mask stops rod cells in the retina from dark adapting, which is thought to reduce their oxygen requirement, which in turn diminishes new blood vessel formation and thus prevents diabetic retinopathy.
C-peptide (?? ????????)
C-peptide had shown promising results in the treatment of diabetic complications incidental to vascular degeneration. Creative Peptides, Eli Lilly, and Cebix all had drug development programs for a C-peptide product.
Stem cell therapy (????? ??? ????????)
Clinical trials are underway or are being populated in preparation for study at medical centers in Brazil, Iran, and the United States. Current trials involve using the patients’ own stem cells derived from bone marrow and injected into the degenerated areas in an effort to regenerate the vascular system.
Fundoscopic image analyses (??????????? ??? ????????)
Diabetic retinopathy is diagnosed entirely by recognizing abnormalities on retinal images taken by fundoscopy. Color fundus photography is mainly used for staging the disease. Fluorescein angiography is used to assess the extent of retinopathy that aids in treatment plan development. Optical coherence tomography (OCT) is used to determine the severity of edema and treatment response.
Diabetic Retinopathy & Free Siddha Energy Remedies (?????? ?????????? ?? ??:????? ????? ????? ?????)
Siddha energy remedies to be applied from day one of the diabetic retinopathy confirmed. The following suggested and tested remedies by applied as a regular activity. If a person is trained in Swami Hardas Life System, he/she knows everything about what is called UAM and should apply regularly over the eyes, which would help solve the problem as well as avoid complications of diabetic retinopathy also. However, those, who are not trained should apply the remedies which include:
DISCLAIMER
The opinions expressed in this article are the personal opinions of the concerned site owners. Siddha Spirituality For Health is not responsible for the accuracy, completeness, suitability, or validity of any information on this article. However, it is advisable to consult a specialist in the concerned field before availing the benefits. Hence we do not assume any responsibility or liability for the same.
Reference: https://en.wikipedia.org/wiki/Diabetic_retinopathy
Really wonderful, detailed, and useful information… Thanx & wishes
Naresh Shandilya 9711299636
President,
New World Foundation
New Delhi
Had no idea that diabetes also affects eye. Thanks for the post.
Precious informatio. Many people dont know about. Can aswami hardas life system cure such eye problems?