Integumentary System Clinical Significance

The integumentary system (पूर्णांक प्रणाली) comprises the skin and its appendages acting to protect the body from various kinds of damage, such as loss of water or damages from outside. The integumentary system includes hair, scales, feathers, hooves, and nails. It has a variety of additional functions; it may serve to waterproof, and protect the deeper tissues, excrete wastes, and regulate body temperature, and is the attachment site for sensory receptors to detect pain, sensation, pressure, and temperature. In most land vertebrates with significant exposure to sunlight, the integumentary system also provides for vitamin D synthesis. This being one of the most important systems, Siddha Spirituality of Swami Hardas Life System appeals to our readers to know in-depth about the integumentary system.

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Integumentary system Organs (पूर्णांक प्रणाली के अंग)

Skin (त्वचा)

The skin is the largest organ of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5-2m2 of surface area.

Human skin (integument) is composed of at least two major layers of tissue: the epidermis and dermis. The epidermis is the outermost layer, providing the initial barrier to the external environment. It is separated from the dermis by the basement membrane. The epidermis contains melanocytes and gives color to the skin.

The deepest layer of the epidermis also contains nerve endings. Beneath this, the dermis comprises two sections, the papillary and reticular layers, and contains connective tissues, vessels, glands, follicles, hair roots, sensory nerve endings, and muscular tissue. The hypodermis is primarily made up of adipose tissue. Substantial collagen bundles anchor the dermis to the hypodermis in a way that permits most areas of the skin to move freely over the deeper tissue layers.

Epidermis (एपिडर्मिस)

The epidermis is the top layer of skin made up of epithelial cells. It does not contain blood vessels. Its main functions are protection, absorption of nutrients, and homeostasis. In structure, it consists of a keratinized stratified squamous epithelium; four types of cells:

  • Keratinocytes
  • Melanocytes
  • Merkel cells, and
  • Langerhans cells

A major cell of the epidermis is the keratinocyte, which produces keratin, a fibrous protein that aids in skin protection.

An overwhelming amount of keratin can cause disease by giving rise to eruptions from the skin that will protrude outwards and lead to infection. Keratin is also a waterproofing protein. Millions of dead keratinocytes rub off daily. The maximum of the skin on the body is keratinized. However, the only skin on the body that is non-keratinized is the lining of mucous membranes, such as the inside of the mouth. Non-keratinized cells allow water to stay atop the structure.

Nails (नाखून)

The protein keratin stiffens epidermal tissue to form fingernails. Nails grow from a thin area called the nail matrix at an average of 1 mm per week. The lunula is the crescent-shape area at the base of the nail, lighter in color as it mixes with the matrix cells. Also, the stratum corneum is the top part of the epidermis.

Dermis (अंतरत्‍वक)

The dermis is the middle layer of skin, composed of dense irregular connective tissue and areolar connective tissue such as collagen with elastin arranged in a diffusely bundled and woven pattern. The dermis has two layers. One is the papillary layer which is the superficial layer and consists of the areolar connective tissue. The other is the reticular layer which is the deep layer of the dermis and consists of the dense irregular connective tissue.

These layers serve to give elasticity to the integument, allowing stretching and conferring flexibility, while also resisting distortions, wrinkling, and sagging. The dermal layer provides a site for the endings of blood vessels and nerves. Many chromatophores are also stored in this layer, as are the bases of integumental structures such as hair, feathers, and glands.

Hypodermis (हापोडर्मिज)

The hypodermis, otherwise known as the subcutaneous layer, is a layer beneath the skin. Hypodermis acts as an energy reserve, which participates, passively at least, in thermoregulation since fat is a heat insulator.

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Integumentary System Function

Integumentary system Functions (पूर्णांक प्रणाली का कार्य)

The integumentary system has multiple roles in homeostasis. All body systems work in an interconnected manner to maintain the internal conditions essential to the function of the body. The skin has an important job of protecting the body and acts as the body’s first line of defense against infection, temperature change, and other challenges to homeostasis. Functions include:

  • Protect the body’s internal living tissues and organs
  • Secure against invasion by infectious organisms
  • Protected from dehydration
  • Protect the body against abrupt changes in temperature, maintain homeostasis
  • Help excrete waste materials through perspiration
  • Act as a receptor for touch, pressure, pain, heat, and cold 
  • Protect the body against sunburns by secreting melanin
  • Generate vitamin D through exposure to ultraviolet light
  • Store water, fat, glucose, vitamin D
  • Maintenance of the body form
  • Formation of new cells from stratum germanium to repair minor injuries
  • Protect from UV rays
  • Regulates body temperature

It distinguishes, separates, and protects the organism from its surroundings. Small-bodied invertebrates of aquatic or continually moist habitats respire using the outer layer. The gas exchange system is called an integumentary exchange, where gases simply diffuse into and out of the interstitial fluid.

Integumentary system Clinical significance (पूर्णांक प्रणाली का नैदानिक महत्व)

Possible diseases and injuries to the human integumentary system include:

  • Rash
  • Yeast
  • Athlete’s foot
  • Infection
  • Sunburn
  • Skin cancer
  • Albinism
  • Acne
  • Herpes
  • Herpes labialis commonly called cold sores
  • Impetigo
  • Rubella
  • Cancer
  • Psoriasis
  • Rabies
  • Rosacea
  • Atopic dermatitis
  • Eczema



6 thoughts on “Integumentary System Clinical Significance

    1. I am overwhelmed to know that you found this article useful. Thanks for your good words, Gajanan. Please enhance your knowledge and also share it with others.

    1. Thanks, Doctor. All of the systems are quite important for the better functioning of human body, which you can better realize. However, I feel it is my prime duty to make people aware of and know about themselves. My efforts are appreciated by authentic people like you for which I am grateful. Thanks a lot.

  1. I feel there are many systems in the human body, which plays important role for a human to perform well. Your efforts to make us aware about self are praiseworthy. Amazing articles. Thanks.

    1. Yes, rightly said Madam! Every system of the human body has its own performance, which is vital for a human body to perform. Any of the systems get disturbed due to some problems, the body as a whole gets affected by various diseases. Hence, we need to understand the systems and our responsibilities towards them, which is quite important for our wellbeing. Thanks for your nice words. Please be in touch and keep enhancing your knowledge ad utilizing for your wellbeing.

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