The immune system (प्रतिरक्षा प्रणाली) is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism’s own healthy tissue. In many species, there are two major subsystems of the immune system: the innate immune system and the adaptive immune system. Siddha Spirituality of Swami Hardas Life System considers the immune system most important of the human body. However, please read this article not only for fun but know about how it affects the body and how to correct or maintain it without money, medicines, and side-effects.
Immune system Definition (प्रतिरक्षा प्रणाली की परिभाषा)
The immune system is the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue, macrophages, lymphocytes including the B cells and T cells, and antibodies.
Immune system Layered defense (प्रतिरक्षा प्रणाली की स्तरित रक्षा)
The immune system protects organisms from infection with layered defenses of increasing specificity. In simple terms, physical barriers prevent pathogens such as bacteria and viruses from entering the organism. If a pathogen breaches these barriers, the innate immune system provides an immediate, but a non-specific response. Innate immune systems are found in all plants and animals. If pathogens successfully evade the innate response, vertebrates possess a second layer of protection, the adaptive immune system, which is activated by the innate response.
Here, the immune system adapts its response during an infection to improve its recognition of the pathogen. The components of the immune system are explained in the following table:
|Innate immune system||Adaptive immune system|
|Response is non-specific||Pathogen and antigen-specific response|
|Exposure leads to immediate maximal response||The lag time between exposure and maximal response|
|Cell-mediated and humoral components||Cell-mediated and humoral components|
|No immunological memory||Exposure leads to immunological memory|
|Found in nearly all forms of life||Found only in jawed vertebrates|
Both innate and adaptive immunity depend on the ability of the immune system to distinguish between self and non-self molecules. In immunology, self molecules are those components of an organism’s body that can be distinguished from foreign substances by the immune system. Conversely, non-self molecules are those recognized as foreign molecules.
Immune system Infants (शिशुओं की प्रतिरक्षा प्रणाली)
Newborn infants have no prior exposure to microbes and are particularly vulnerable to infection. Several layers of passive protection are provided by the mother. During pregnancy, a particular type of antibody, called IgG, is transported from mother to baby directly through the placenta, so human babies have high levels of antibodies even at birth, with the same range of antigen specificities as their mother.
Breast milk or colostrum also contains antibodies that are transferred to the gut of the infant and protect against bacterial infections until the newborn can synthesize its own antibodies. This is passive immunity because the fetus does not actually make any memory cells or antibodies—it only borrows them.
Innate immune system (रोगप्रतिरोधक प्रणाली)
Microorganisms or toxins that successfully enter an organism encounter the cells and mechanisms of the innate immune system. The innate response is usually triggered when microbes are identified by pattern recognition receptors, which recognize components that are conserved among broad groups of microorganisms, or when damaged, injured or stressed cells send out alarm signals, many of which are recognized by the same receptors as those that recognize pathogens.
Innate immune defenses are non-specific, meaning these systems respond to pathogens in a generic way. This system does not confer long-lasting immunity against a pathogen. The innate immune system is the dominant system of host defense in most organisms.
Adaptive immune system (अनुकूली प्रतिरक्षा प्रणाली)
The adaptive immune system evolved in early vertebrates and allows for a stronger immune response as well as immunological memory. The adaptive immune response is antigen-specific and requires the recognition of specific “non-self” antigens during a process called antigen presentation.
Immune system Physiological regulation (प्रतिरक्षा प्रणाली का शारीरिक विनियमन)
The immune system is involved in many aspects of physiological regulation in the body, which interacts intimately with other systems, such as the endocrine and the nervous systems. It also plays a crucial role in embryogenesis, as well as in tissue repair and regeneration.
Hormones can act as immunomodulators, altering the sensitivity of the immune system. For example, female sex hormones are known as immunostimulators of both adaptive and innate immune responses. Some autoimmune diseases such as lupus erythematosus strike women preferentially, and their onset often coincides with puberty. By contrast, male sex hormones such as testosterone seem to be immunosuppressive. Other hormones appear to regulate the immune system as well, most notably prolactin, growth hormone, and vitamin D.
Vitamin D (विटामिन डी)
When a T-cell encounters a foreign pathogen, it extends a vitamin D receptor. This is essentially a signaling device that allows the T-cell to bind to the active form of vitamin D, the steroid hormone calcitriol. T-cells have a symbiotic relationship with vitamin D.
It is conjectured that a progressive decline in hormone levels with age is partially responsible for weakened immune responses in aging individuals. Conversely, some hormones are regulated by the immune system, notably thyroid hormone activity. The age-related decline in immune function is also related to decreasing vitamin D levels in the elderly.
As people age, two things happen that negatively affect their vitamin D levels. First, they stay indoors more due to decreased activity levels. This means that they get less sun and therefore produce less cholecalciferol via UVB radiation. Second, as a person ages, the skin becomes less adept at producing vitamin D.
Sleep and rest (सोयें और आराम करें)
The immune system is affected by sleep and rest, and sleep deprivation is detrimental to immune function. Complex feedback loops involving cytokines, such as interleukin-1 and tumor necrosis factor-α produced in response to infection, appear to also play a role in the regulation of non-rapid eye movement (REM) sleep. Thus the immune response to infection may result in changes to the sleep cycle, including an increase in slow-wave sleep relative to REM sleep.
When suffering from sleep deprivation, active immunizations may have a diminished effect and may result in lower antibody production, and a lower immune response, than would be noted in a well-rested individual. Additionally, proteins such as NFIL3, which have been shown to be closely intertwined with both T-cell differentiation and our circadian rhythms, can be effected through the disturbance of natural light and dark cycles through instances of sleep deprivation, shift work, etc. As a result, these disruptions can lead to an increase in chronic conditions such as heart disease, chronic pain, and asthma.
In contrast, during wake periods differentiated effector cells, such as cytotoxic natural killer cells and CTLs (cytotoxic T lymphocytes), peak in order to elicit an effective response against any intruding pathogens. As well during awake active times, anti-inflammatory molecules, such as cortisol and catecholamines, peak.
Nutrition and diet (पोषण और आहार)
Overnutrition is associated with diseases such as diabetes and obesity, which are known to affect immune function. More moderate malnutrition, as well as a certain specific trace mineral and nutrient deficiencies, can also compromise the immune response.
Foods rich in certain fatty acids may foster a healthy immune system. Likewise, fetal undernourishment can cause a lifelong impairment of the immune system.
Repair and regeneration (मरम्मत और पुनर्जनन)
The immune system, particularly the innate component, plays a decisive role in tissue repair after an insult. Key actors include macrophages and neutrophils, but other cellular actors, including γδ T cells, innate lymphoid cells (ILCs), and regulatory T cells (Tregs), are also important. The plasticity of immune cells and the balance between pro-inflammatory and anti-inflammatory signals are crucial aspects of efficient tissue repair.
According to one hypothesis, organisms that can regenerate could be less immunocompetent than organisms that cannot regenerate.
Human immunity system Disorders (मानव प्रतिरक्षा प्रणाली विकार)
The immune system is a remarkably effective structure that incorporates specificity, inducibility, and adaptation. Failures of host defense do occur, however, and fall into three broad categories: immunodeficiencies, autoimmunity, and hypersensitivities.
Immunodeficiencies occur when one or more of the components of the immune system are inactive. The ability of the immune system to respond to pathogens is diminished in both the young and the elderly, with immune responses beginning to decline at around 50 years of age due to immunosenescence.
In developed countries, obesity, alcoholism, and drug use are common causes of poor immune function. However, malnutrition is the most common cause of immunodeficiency in developing countries. Diets lacking sufficient protein are associated with impaired cell-mediated immunity, complement activity, phagocyte function, IgA antibody concentrations, and cytokine production.
Overactive immune responses comprise the other end of immune dysfunction, particularly the autoimmune disorders. Here, the immune system fails to properly distinguish between self and non-self and attacks part of the body. Under normal circumstances, many T cells and antibodies react with “self” peptides. One of the functions of specialized cells is to present young lymphocytes with self-antigens produced throughout the body and to eliminate those cells that recognize self-antigens, preventing autoimmunity.
Hypersensitivity is an immune response that damages the body’s own tissues. These are divided into four classes (Type I – IV) based on the mechanisms involved and the time course of the hypersensitive reaction:
Type I hypersensitivity (टाइप I अतिसंवेदनशीलता)
It is an immediate or anaphylactic reaction, often associated with allergy. Symptoms can range from mild discomfort to death.
Type II hypersensitivity (टाइप II अतिसंवेदनशीलता)
When antibodies bind to antigens on the patient’s own cells, marking them for destruction, Type II hypersensitivity occurs.
Type III hypersensitivity (टाइप III अतिसंवेदनशीलता)
Immune complexes (aggregations of antigens, complement proteins, and IgG and IgM antibodies) deposited in various tissues trigger Type III hypersensitivity reactions.
Type IV hypersensitivity (टाइप IV अतिसंवेदनशीलता)
Hypersensitivity of type IV usually takes between two and three days to develop.
Idiopathic inflammation (अज्ञातहेतुक सूजन)
Inflammation is one of the first responses of the immune system to infection, but it can appear without a known cause. Eicosanoids include prostaglandins that produce fever and the dilation of blood vessels associated with inflammation and leukotrienes that attract certain white blood cells.
Common cytokines include interleukins that are responsible for communication between white blood cells; chemokines that promote chemotaxis; and interferons that have anti-viral effects, such as shutting down protein synthesis in the host cell.
Manipulation in medicine (चिकित्सा में हेरफेर)
The immune response can be manipulated to suppress unwanted responses resulting from autoimmunity, allergy, and transplant rejection:
These drugs are used to control autoimmune disorders or inflammation when excessive tissue damage occurs. Glucocorticoids are the most powerful of these drugs; however, these drugs can have many undesirable side effects, such as central obesity, hyperglycemia, osteoporosis, and their use must be tightly controlled.
Immunostimulation (रोगप्रतिकारक शक्ती)
Cancer immunotherapy covers medical ways to stimulate the immune system to attack cancer tumors.
Long-term active memory is acquired following infection by activation of B and T cells. Active immunity can also be generated artificially, through vaccination. The principle behind vaccination is to introduce an antigen from a pathogen in order to stimulate the immune system and develop specific immunity against that particular pathogen without causing disease associated with that organism.
This deliberate induction of an immune response is successful because it exploits the natural specificity of the immune system, as well as its inducibility. With infectious disease remaining one of the leading causes of death in the human population, vaccination represents the most effective manipulation of the immune system mankind has developed.
Tumor immunology (ट्यूमर प्रतिरक्षा)
Another important role of the immune system is to identify and eliminate tumors. This is called immune surveillance. The transformed cells of tumors express antigens that are not found on normal cells. To the immune system, these antigens appear foreign, and their presence causes immune cells to attack the transformed tumor cells.
Predicting immunogenicity (प्रतिरक्षाजनकता का पूर्वानुमान)
Larger drugs (>500 Da) can provoke a neutralizing immune response, particularly if the drugs are administered repeatedly, or in larger doses. This limits the effectiveness of drugs based on larger peptides and proteins (which are typically larger than 6000 Da). In some cases, the drug itself is not immunogenic but may be co-administered with an immunogenic compound, as is sometimes the case for Taxol.
Computational methods have been developed to predict the immunogenicity of peptides and proteins, which are particularly useful in designing therapeutic antibodies, assessing likely virulence of mutations in viral coat particles, and validation of proposed peptide-based drug treatments.
Immune system booster (प्रतिरक्षा प्रणाली बूस्टर)
Your lifestyle can affect how well your immune system can protect you from germs, viruses, and chronic illness. Replacing bad health habits with good ones can help keep your immune system healthy. Check this list to see where you could use some improvement.
Shortage of sleep (नींद की कमी)
You may have noticed you’re more likely to catch a cold or other infection when you’re not getting enough sleep. Studies help bear out that well-rested people who received the flu vaccine developed stronger protection against the illness. Not getting enough sleep can lead to higher levels of a stress hormone. It may also lead to more inflammation in your body.
Although researchers aren’t exactly sure how sleep boosts the immune system, it’s clear that getting enough – usually 7 to 9 hours for an adult – is key for good health.
Exercise to fight the immune system (प्रतिरक्षा प्रणाली से लड़ने के लिए व्यायाम)
Try to get regular, moderate exercise, like a daily 30-minute walk. It can help your immune system fight infection. If you don’t exercise regularly, you’re more likely to get colds, for example, than someone who does. Exercise can also boost your body’s feel-good chemicals and help you sleep better. Both of those are good for your immune system.
A healthy diet (स्वस्थ आहार)
Eating or drinking too much sugar curbs immune system cells that attack bacteria. This effect lasts for at least a few hours after downing a couple of sugary drinks.
Eat more fruits and vegetables, which are rich in nutrients like vitamins C and E, plus beta-carotene and zinc. Go for a wide variety of brightly colored fruits and vegetables, including berries, citrus fruits, kiwi, apples, red grapes, kale, onions, spinach, sweet potatoes, and carrots.
Other foods particularly good for your immune system include fresh garlic, which may help fight viruses and bacteria, and old-fashioned chicken soup. If you do come down with a cold or the flu, a bowl of chicken soup can help you get well faster, one study shows.
Everyone has some stress; it’s part of life. If stress drags on for a long time, it makes you more vulnerable to illness, from colds to serious diseases. Chronic stress exposes your body to a steady stream of stress hormones that suppress the immune system.
You may not be able to get rid of your stress, but you can get better at managing it:
- Learn to meditate
- Slow down
- Connect with other people
- Work out to blow off steam
- Counseling is a big help
Easing stress lowers levels of a stress hormone. It also helps you sleep better, which improves immune function.
People who meditate regularly may have healthier immune system responses, some studies show. In one experiment, people who meditated over an 8-week period made more antibodies to a flu vaccine than people who didn’t meditate.
Good social network (अच्छा सामाजिक नेटवर्क)
Having strong relationships and a good social network is good for you. In one study, lonely freshmen had a weaker immune response to a flu vaccine than those who felt connected to others. Although there are many other things that affect your health, making meaningful connections with people is always a good idea.
Losing sense of humor (हास्य की भावना खोना)
Laughing is good for you. It curbs the levels of stress hormones in your body and boosts a type of white blood cell that fights infection. Just anticipating a funny event can have a positive effect on your immune system.
Immune system & Free Siddha energy remedies (प्रतिरक्षा प्रणाली और नि:शुल्क सिद्ध ऊर्जा उपचार)
1. Siddha preventive measures (सिद्ध निवारक उपाय)
Everybody must practice Siddha preventive measures, whether a person is affected with the immune system or not, but preventive measures are the primary steps for switching on to any other Siddha energy remedies, and hence they are important. It helps in one’s capability, effectiveness, and productivity, decision making power, intellectuality and removing minor health problems. There are three types of preventive measures:
- Earthing – performed for earthing the negativity of our body
- Field Cleaning – cleans energy field (Aura) of our body
- Siddha Brain Exercise/Energizing – energizes our brain for proper functionality
Everybody’s tendency is to get attracted to the word ‘free‘, however, don’t neglect even these Siddha preventive measures are free. Avail the benefits by practicing them sincerely, and regularly. For the ease of understanding Siddha preventive measures, please watch a video for a live demonstration.
2. Siddha Shaktidata Yog (सिद्ध शक्तीदाता योग)
This unique Siddha Shaktidata Yog of Siddha Spirituality can solve the problems related to the immune systemwith free Siddha energy remedies. There is no compulsion of training of ‘Swami Hardas Life System’ methods. This not only gives benefits to self but also it can be used for other affected persons, whether a person is in the same house, distantly available in the same city, same nation or might be in any corner of the world, however, both the procedures have been explained here.
3. Siddha Kalyan Sadhana (सिद्ध कल्याण साधना)
Recite this Sadhana with a Sankalp “My problems of the immune system are solved as early as possible and I should gain health”, which should be repeated in mind 3 – 3 times every after each stanza. Any person irrespective of caste, creed, religion, faith, sex, and age can recite this Sadhana for free, which should be repeated at least twice in a day. To know more, please click on this link.
A daily routine (एक दैनिक दिनचर्या)
In general, a daily routine to manage the immune system may look like this:
- Carry out all medical checks as suggested above and follow the advice of your doctor
- Apply free Siddha energy remedies minimum 3 times a day, as explained above
- Bring some lifestyle changes i.e. regular exercise, healthy diet
- Do walking minimum for 30 minutes daily
- Try to undergo advanced training of Swami Hardas Life System for fast recovery
- Perform Swayamsiddha Agnihotra daily as it promises to purify air pollution and imparts numerous benefits
Ensure to sprinkle in some fun during the day: Don’t forget to relax and laugh in between. Laughing is a great way to boost your immune system and help you.
Along with all the above activities, apply above explained free Siddha energy remedies minimum 3 times a day, the more is good. Just try the methods of Siddha Spirituality of Swami Hardas Life System. I am confident that you will surely find improvements within 15 days.
Training of Swami Hardas Life System (स्वामी हरदास लाइफ सिस्टम का प्रशिक्षण)
Any problem with regard to health, peace, and progress can be solved independently without money and medicines by undergoing training of Swami Hardas Life System. Any person irrespective of religion, caste, creed, faith, sex, and age can undergo this unique training.
In view of the above, I am confident that you have learned about the immune system, definition, layered defense, innate immune system, adaptive immune system, human immunity disorders, booster, vaccination, types of hypersensitivity, and medications. You also learned free Siddha energy remedies. Now, you have become self-sufficient, hence its right time to use your acquired knowledge for solving problems as per the provision available in Siddha Spirituality of Swami Hardas Life System.
After reading this article, what are your thoughts? Would you please put more efforts into enhancing or updating your knowledge? Please let me know your precious thoughts.
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