Progressive supranuclear palsy (PSP) [प्रगतिशील सुपरन्यूक्लियर पक्षाघात] is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain. The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and dementia. PSP may be mistaken for other neurodegenerative diseases such as Parkinson’s and Alzheimer’s. The cause of the condition is uncertain but involves the accumulation of tau protein within the brain. Medications such as levodopa and amantadine may be useful in some cases. PSP affects about six people per 100,000. Hence, Siddha Spirituality of Swami Hardas Life System considers PSP one of the most dreaded diseases.
Progressive supranuclear palsy Definition (प्रगतिशील सुपरन्यूक्लियर पक्षाघात की परिभाषा)
PSP is a movement disorder that occurs from damage to certain nerve cells in the brain. PSP is a condition that causes symptoms similar to those of Parkinson’s disease. It involves damage to many cells of the brain.
Progressive supranuclear palsy Symptoms (प्रगतिशील सुपरन्यूक्लियर पक्षाघात के लक्षण)
The initial symptoms in two-thirds of cases are loss of balance, lunging forward when mobilizing, fast walking, bumping into objects or people, and falls. Dementia symptoms are also initially seen in about one in five cases.
Other common early symptoms are changes in personality, a general slowing of movement, and visual symptoms. The most common behavioral symptoms in patients with PSP include apathy, disinhibition, anxiety, dysphoria.
Later symptoms and signs are dementia, slurring of speech, difficulty swallowing, and difficulty moving the eyes, particularly in the vertical direction. The latter accounts for some of the falls experienced by these patients, as they are unable to look up or down.
Some of the other signs are poor eyelid function, contracture of the facial muscles, a backward tilt of the head with stiffening of the neck muscles, sleep disruption, urinary incontinence, and constipation.
The visual symptoms are of particular importance in the diagnosis of this disorder. Patients typically complain of difficulty reading due to the inability to look down well.
Progressive supranuclear palsy Causes (प्रगतिशील सुपरन्यूक्लियर पक्षाघात के कारण)
The causes of the PSP are unknown. Fewer than 1% of those with PSP have a family member with the same disorder.
A variant in the gene for tau protein called the H1 haplotype, located on chromosome 17, has been linked to PSP. Nearly all people with PSP received a copy of that variant from each parent, but this is true of about two-thirds of the general population. Besides tauopathy, mitochondrial dysfunction seems to be a factor involved in PSP.
Progressive supranuclear palsy Pathophysiology (प्रगतिशील सुपरन्यूक्लियर पक्षाघात की पैथोफिजियोलॉजी)
The affected brain cells are both neurons and glial cells. The neurons display neurofibrillary tangles (NFTs), which are clumps of tau protein, a normal part of a brain cell’s internal structural skeleton. These tangles are often different from those seen in Alzheimer’s disease, but maybe structurally similar when they occur in the cerebral cortex. Their chemical composition is usually different, however, and is similar to that of tangles seen in corticobasal degeneration.
Unlike globose NFTs, they may be more widespread in the cortex. Lewy bodies are seen in some cases, but whether this is a variant or an independent co-existing process is not clear, and in some cases, PSP can coexist with corticobasal degeneration, Parkinson’s, and/or Alzheimer’s disease, particularly with older patients.
The principal areas of the brain affected are the:
- Basal ganglia, particularly the subthalamic nucleus, substantia nigra, and globus pallidus
- Brainstem, particularly the portion of the midbrain where “supranuclear” eye movement resides
- Cerebral cortex, particularly that of the frontal lobes
- A Dentate nucleus of the cerebellum
- The spinal cord, particularly the area where some control of the bladder and bowel resides
Some consider PSP, corticobasal degeneration, and frontotemporal dementia to be variations of the same disease. Others consider them separate diseases. PSP has been shown occasionally to co-exist with Pick’s disease.
Progressive supranuclear palsy Diagnosis (प्रगतिशील सुपरन्यूक्लियर पक्षाघात का निदान)
MRI may show atrophy in the midbrain with preservation of the pons giving a “hummingbird” sign appearance and Mickey Mouse sign.
Progressive supranuclear palsy Types (प्रगतिशील सुपरन्यूक्लियर पक्षाघात के प्रकार)
Four known categories of PSP include:
- Classical Richardson syndrome (PSP-RS)
- PSP-parkinsonism (PSP-P) and PSP-pure akinesia with gait freezing (PSP-PAGF)
- Frontal PSP, PSP-corticobasal syndrome (PSP-CBS), PSP-behavioural variant of frontotemporal dementia (PSP-bvFTD) and PSP-progressive non-fluent aphasia (PSP-PNFA)
The typical features of PSP characterize Richardson syndrome. PSP-P features of Parkinson’s Disease overlap with the clinical presentation of PSP and follow a more benign course. In both PSP-P and PSP- PAGF distribution of abnormal tau is relatively restricted to the brain stem. Frontal PSP initially presents with behavioral and cognitive symptoms, with or without ophthalmoparesis, and then evolves into typical PSP.
Progressive supranuclear palsy Differential diagnosis (प्रगतिशील सुपरन्यूक्लियर पक्षाघात का विभेदक निदान)
PSP is frequently misdiagnosed as Parkinson’s disease because they both involve slowed movements and gait difficulty, with PSP being one of a collection of diseases referred to as Parkinson plus syndromes. Both Parkinson’s and PSP have an onset in late middle age and involve slowing and rigidity of movement. However, several distinguishing features exist. Tremor is very common with Parkinson’s, but rare with PSP.
Speech and swallowing difficulties are more common and severe with PSP, and the abnormal eye movements of PSP are essentially absent with PD. A poor response to levodopa along with symmetrical onset can also help differentiate PSP from PD. Patients with the Richardson variant of PSP tend to have an upright posture or arched back, as opposed to the stooped-forward posture of other Parkinsonian disorders, although PSP-Parkinsonism can demonstrate a stooped posture. Early falls are also more common with PSP, especially with Richardson syndrome.
Progressive supranuclear palsy Treatment (प्रगतिशील सुपरन्यूक्लियर पक्षाघात का उपचार)
Two subgroups of PSP include:
- PSP-Richardson, the classic type, and
Dyskinesia is an occasional but rare complication of treatment. Amantadine is also sometimes helpful. After a few years, the Parkinsonian variant tends to take on Richardson features. Other variants have been described. Botox can be used to treat neck dystonia and blepharospasm, but this can aggravate dysphagia.
Patients with PSP usually seek or are referred to occupational therapy, speech-language pathology for motor speech changes typically spastic-ataxic dysarthria, and physical therapy for balance and gait problems with reports of frequent falls. Evidence-based approaches to rehabilitation in PSP are lacking, and currently, the majority of research on the subject consists of case reports involving only a small number of patients.
Case reports of rehabilitation programs for patients with PSP generally include:
- Limb-coordination activities
- Tilt-board balancing, gait training
- Strength training with progressive resistive exercises
- Isokinetic exercises and stretching of the neck muscles
While some case reports suggest that physiotherapy can offer improvements in balance and gait of patients with PSP, the results cannot be generalized across all PSP patients, as each case report only followed one or two patients. The observations made from these case studies can be useful.
Individuals with PSP are often referred to occupational therapists to help manage their condition and to help enhance their independence. This may include being taught to use mobility aids. Due to their tendency to fall backward, the use of a walker, particularly one that can be weighted in the front, is recommended over a cane. The use of an appropriate mobility aid helps to decrease the individual’s risk of falls and makes them safer to ambulate independently in the community. Due to their balance problems and irregular movements, individuals need to spend time learning how to safely transfer in their homes and in the community. This may include rising from and sitting in chairs safely.
Due to the progressive nature of this disease, all individuals eventually lose their ability to walk and will need to progress to using a wheelchair. Severe dysphagia often follows, and at this point, death is often a matter of months.
Progressive supranuclear palsy Prognosis (प्रगतिशील सुपरन्यूक्लियर पक्षाघात का पूर्वानुमान)
The average age at symptoms onset is 63, and survival from onset averages 7 years with a wide variance. Pneumonia is a frequent cause of death.
Progressive supranuclear palsy & Free Siddha energy remedies (प्रगतिशील सुपरन्यूक्लियर पक्षाघात और नि:शुल्क सिद्ध ऊर्जा उपचार)
1. Siddha preventive measures (सिद्ध निवारक उपाय)
Everybody must practice Siddha preventive measures, whether a person is affected with progressive supranuclear palsy or not, but preventive measures are the primary steps for switching on to any other Siddha energy remedies, and hence they are important. It helps in one’s capability, effectiveness, and productivity, decision making power, intellectualism, and removing minor health problems. There are three types of preventive measures:
- Earthing – performed for earthing the negativity of our body
- Field Cleaning – cleans energy field (Aura) of our body
- Siddha Brain Exercise/Energizing – energizes our brain for proper functionality
Everybody’s tendency is to get attracted to the word ‘free‘, however, don’t neglect even these Siddha preventive measures are free. Avail the benefits by practicing them sincerely, and regularly. For the ease of understanding what Siddha preventive measures are, please watch a video for a live demonstration.
2. Siddha Shaktidata Yog (सिद्ध शक्तीदाता योग)
This unique Siddha Shaktidata Yog of Siddha Spirituality can solve the problems related to progressive supranuclear palsy with free Siddha energy remedies. There is no compulsion of training of ‘Swami Hardas Life System’ methods. This not only gives benefits to self but also it can be used for other affected persons, whether a person is in the same house, distantly available in the same city, same nation or might be in any corner of the world, however, both the procedures have been explained here.
3. Siddha Kalyan Sadhana (सिद्ध कल्याण साधना)
Recite this Sadhana with a Sankalp “My problems of progressive supranuclear palsy are solved as early as possible and I should gain health”, which should be repeated in mind 3 – 3 times every after each stanza. Any person irrespective of caste, creed, religion, faith, sex, and age can recite this Sadhana for free, which should be repeated at least twice in a day. To know more, please click on this link.
4. CCPE products (CCPE उत्पाद)
These products work on the concepts of ‘Conceptual Creative Positive Energy’ (CCPE) within the provisions of the ‘CCPE Life System’ and the theory of Quantum Technology to a certain extent. However, the products get activated only whenever touched by a human and then they become capable of solving the problem and achieving health. However, please use these products for progressive supranuclear palsy as mentioned below:
CCPE Extractor: The CCPE Extractor should be gently moved over the Agya Chakra in a circular motion at least for 30 to 60 seconds, thereafter, follow the same process on the head, heart, and naval for another 30 to 60 seconds, which finishes within almost 2 – 4 minutes.
CCPE Booster: Keep one Booster over the Agya Chakra and another one each over the head, heart, and naval for 3 – 6 minutes. You may need to have 4 Boosters, which establishes positivity.
5. A daily routine for dehydration (निर्जलीकरण के लिए एक दैनिक दिनचर्या)
In general, a daily routine may look like this:
- Approach your Doctor and follow the advice
- Apply free Siddha energy remedies minimum 3 times a day, as explained above
- Do Ananda Sadhana daily (irrespective of belonging to any religion)
- Perform Swayamsiddha Agnihotra daily, if feasible
- In case, if someone wishes to learn advanced methods of Swami Hardas Life System, undergo unique training
Ensure to sprinkle in some fun during the day: Don’t forget to relax and laugh in between. Laughing is a great way to boost your immune system and help you.
Along with all the above activities, apply above explained free Siddha energy remedies minimum 3 times a day, the more is good. Just try the methods of Siddha Spirituality of Swami Hardas Life System. I am confident that you will surely find improvements within 3 days.
Training of Swami Hardas Life System (स्वामी हरदास लाइफ सिस्टम का प्रशिक्षण)
Any problem with regard to health, peace, and progress can be solved independently without money and medicines by undergoing training of Swami Hardas Life System. Any person irrespective of religion, caste, creed, faith, sex, and age can undergo this unique training.
In view of the above, I am confident that you have learned about the progressive supranuclear palsy, definition, symptoms, causes, types, diagnosis, and treatment. You also learned free Siddha energy remedies. Now, you have become self-sufficient, hence its right time to use your acquired knowledge for solving problems as per the provision available in Siddha Spirituality of Swami Hardas Life System.
After reading this article, how would you rate it? Would you please let me know your precious thoughts?
The opinions expressed in this article are the personal opinions of the concerned site owners. Siddha Spirituality For Health is not responsible for the accuracy, completeness, suitability, or validity of any information on this article. However, it is advisable to consult a specialist in the concerned field before availing of the benefits. Hence we do not assume any responsibility or liability for the same.